TU Delft
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2013/2014 Mechanical, Maritime and Materials Engineering Master Biomedical Engineering
Applied Experimental Methods: Medical Instruments
Responsible Instructor
Name E-mail
Dr. J.J. van den Dobbelsteen    J.J.vandenDobbelsteen@tudelft.nl
Name E-mail
N.J.P. van de Berg    N.J.P.vandeBerg@tudelft.nl
Dr.ir. D.J. van Gerwen    D.J.vanGerwen@tudelft.nl
Contact Hours / Week x/x/x/x
Education Period
Start Education
Exam Period
Course Language
Expected prior knowledge
Admission to MSc phase
Instrument-tissue interaction, minimally invasive techniques, tissue characterization and identification
Course Contents
In this course, students carry out self-contained projects which contribute to our insight in instrument-tissue interactions in the application of minimally invasive techniques such as needle or catheter placement.

Key in this course is that students, in groups of two, identify their individual assignment themselves. You (together with your team partner) will select and define a sub-project that will contribute to solve a part of the very complex problems encountered in above-mentioned research fields. You will set up your own experiment and investigate the response to your experimental manipulations. The results should allow you to draw conclusions that are relevant for the development or improvement of minimally invasive techniques.

Different experimental set-ups are available for precise position control of the instruments. Often other hardware or tissue simulants need to be realized for specific experiments.
Study Goals
The student must be able to:
1 Formulate a self-contained subproject within the framework of a given long-term research project in the field of instrument-tissue interaction:
Get acquainted with background knowledge on the research subject.
Identify a subproject that has sufficient profundity and that can be completed in the allotted time.
Formulate the research questions or objectives without reference to methods or solutions.
2 Execute the self-defined subproject:
Select and apply appropriate research methods.
Create an experimental platform.
Use suitable methods to analyse the data.
Present the results in a concise report and podium presentation.
Self-reflect on intended and actual project outcome.
Education Method
Students preferably work in groups of two. They acquire basic knowledge through self-study, guided by instructors. Subsequently, they define a project that is sufficiently challenging, yet feasible within the allotted timeframe. Finally they execute this self-defined project and conclude with a presentation and a brief report.
The underlying educational idea is that students not only familiarize themselves with a subject that is new to them but also obtain hands-on experience in handling large projects by subdividing them into multiple smaller ones. This experience is useful in their graduation project and future profession.
Computer Use
Depending on individual project between 20 and 80%
Literature and Study Materials
Course material: Blackboard

References from literature:
Depending on individual assignment, reports from previous students, materials in 'Course Documents' folder in Blackboard.
1. About one page containing self-defined project (background, problem statement, research objective, limitations, relevance to overall project) and planning.
2. Intermediate progress presentation.
3. Final presentation (10-15 min).
4. Written report (at most 4 pages, two-column scientific paper format).
The course incorporates a fair amount of self-reliance, and is intended to be Self-Developing in two senses. Firstly, this term emphasizes the responsibility of the students to acquire the appropriate knowledge. Secondly, it indicates that students do not execute predefined projects but rather define and execute small, novel research projects within a larger framework. Thus, the course aims to bridge the gap between regular courses and the graduation project. Meanwhile, the students contribute to major research projects.
Percentage of Design
Design Content
Students will be familiarized with the design of experimental setups and tissue simulants for the study of instrument-tissue interaction.
3mE Department Biomechanical Engineering